Market Access Intelligence.
Built for Decision Speed.

VantEdge Access helps biopharma teams secure reimbursement, strengthen pricing strategy, and anticipate HTA outcomes, through senior-led consulting and three proprietary platforms: OMNIA, PreserveIQ and MFN PRICE.

Evidence-driven. Payer-aligned. Launch-ready.

Senior market access leadership

Pricing, reimbursement, and HEOR expertise

Rare disease and specialty access focus

AI-enabled HTA intelligence across global markets

Our approach

We start where payers start.

We assess evidence through the lens of HTA decision-making, reimbursement constraints, and stakeholder incentives—then design strategies that hold up across markets.

Senior-led execution

No layers. No handoffs. Direct access leadership.

Payer-first thinking

Evidence and positioning built around what payers reward.

Integrated strategy

Clinical development, HEOR, pricing, and access—connected.

AI-enabled speed

OMNIA accelerates analogue intelligence and HTA learning.

Access is strategy.

We help teams treat access planning as a strategic advantage—not a late-stage obstacle.

Speak With Our Team

Incorporated in Illinois with hubs in Chicago⁠/⁠Oak Brook (US) and Paris (FR), VantEdge Access combines proprietary AI with deep consulting expertise across the USA*, Canada, EU-5 and other international markets**, leveraging one of the industry's largest HTA databases with 10,000+ reports and 1,200+ drugs covering all therapeutic areas.

*Covering ICER (Institute for Clinical and Economic Review) HTA reports and private US payer projects on-demand with rapid turnaround times.
**Other international markets include Argentina, Brazil, Australia, and others.

Market Access Strategy

Global and local strategies that align evidence, stakeholders, and reimbursement realities.

Pricing & Value

Defensible pricing corridors grounded in HTA logic and analogue outcomes.

Proprietary Platforms

OMNIA, PreserveIQ and MFN PRICE: evidence, recovery and pricing exposure, connected to enterprise value.

Proprietary platforms

Three proprietary platforms, one connected reimbursement strategy.

Human intelligence, augmented by three purpose-built tools. OMNIA reads the HTA landscape, PreserveIQ recovers value after a negative decision, and MFN PRICE quantifies pricing exposure across markets. Each stands alone; together they connect evidence, recovery and pricing to enterprise value.

10,000+

HTA reports

10

National agencies

1,200+

Drugs, all therapeutic areas

3

Proprietary platforms

OMNIA, HTA intelligence engine

OMNIA™

HTA intelligence engine

Source-linked answers from 10,000+ HTA reports across ten national agencies, with analogue sets, an agentic assistant and a JCA readiness scorecard.

Delivers

  • Cross-country evidence linked to source reports
  • Analogue and competitor sets
  • Answers and draft documents in hours rather than weeks

Applies when

  • Evidence planning, positioning and submissions
  • JCA readiness
  • Due diligence and early commercial assessment
PreserveIQ, value preservation framework

PreserveIQ™

Value preservation framework

A negative decision creates immediate pressure to discount. PreserveIQ diagnoses what blocked reimbursement, tests whether price can solve it, and sequences the response.

Delivers

  • Read of the decision: blockers and leverage
  • Ranked gaps by impact and feasibility
  • Negotiation posture and plan: evidence, then terms, then price

Applies when

  • Negative, restricted or delayed decision
  • Resubmission or appeal in preparation
  • Discount considered as the first response
MFN PRICE, pricing exposure framework

MFN PRICE™

Pricing exposure framework

Most Favored Nation pricing is not one price, it is cross-market transmission. Exposure is scored alongside strategic flexibility, before the launch sequence is fixed.

Delivers

  • Two scores kept apart: exposure and flexibility
  • One management priority: act, build optionality, monitor or accept
  • Market-by-market simulation

Applies when

  • Wide price gap between the US and abroad
  • Launch sequence still open or corridor under review
  • MFN agreement signed or mandatory model in scope

How the three connect

01

Evidence in

OMNIA supplies the precedent: what payers accepted, refused and negotiated.

02

Decisions tested

PreserveIQ and MFN PRICE turn it into a recovery posture and a defensible pricing position.

03

Value protected

Both answer one question: what the decision is worth to the company.

What clients achieve

Stronger payer positioning earlier in development

Faster access planning and launch readiness

More confident pricing and negotiation strategy

Improved alignment across access, medical, and commercial teams

Reduced reimbursement risk across markets

Strategic Access Solutions

Focused engagements built around the decisions that determine reimbursement outcomes.

Early Development & TPP Strategy

Align your clinical development strategy with payer expectations before it becomes expensive to change.

  • TPP optimization
  • Endpoint and comparator strategy
  • Early value story development
  • Payer insights and advisory boards

Pricing & Valuation Strategy

Define pricing corridors that reflect real-world HTA logic and analogue outcomes.

  • Value-based pricing assessment
  • Analogue benchmarking
  • Cross-market pricing strategy
  • Pricing risk and sensitivity analysis

HEOR & Evidence Strategy

Evidence packages built to withstand HTA review and reimbursement scrutiny.

  • Cost-effectiveness modeling (CEA)
  • Budget impact analysis (BIA)
  • RWE strategy and study design
  • HTA-aligned evidence gap planning

Launch Readiness & Access Planning

Structured market access roadmaps across markets and stakeholders.

  • Access readiness assessment
  • Market development plans
  • Stakeholder engagement planning
  • Reimbursement pathway strategy

Access Risk Mitigation

Identify access barriers early. Prioritize them. Solve them.

  • Risk scoring and prioritization
  • Forecast impact assessment
  • Mitigation strategy development
  • Tailored payer solutions

HTA Intelligence & Analytics

Faster insights. Better strategy. Stronger execution.

  • HTA intelligence and analogue analysis
  • Market comparisons and trend insights
  • AI-enabled extraction through OMNIA
  • Export-ready outputs for leadership teams

Reimbursement Recovery

Turn a negative, restricted or delayed decision into a managed recovery.

  • Diagnostic read of the decision as the payer wrote it
  • Test of whether a price concession changes the outcome
  • Gaps ranked by impact and feasibility
  • Negotiation plan through PreserveIQ: evidence, terms, then price

MFN Exposure & Launch Sequencing

Score cross-market pricing exposure before the launch sequence is fixed.

  • Exposure scored on policy, reference price, spillover and impact
  • Strategic flexibility rated: timing, contracting, evidence, sequencing
  • One management priority: act, build optionality, monitor or accept
  • Market-by-market simulation through MFN PRICE

Need clarity on your next access milestone?

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Leadership with real-world access experience.

VantEdge Access is led by market access professionals who have shaped strategy across major pharma, biotech, and specialty markets.

Kasem Akhras

Kasem S Akhras, PharmD

CEO & Co-Founder

Market access executive, strategist, author, and international speaker with deep expertise across pricing, reimbursement, HEOR, and payer engagement.

Well‑published, including the authoritative book Frontiers in Market Access and as contributing author in Development of Gene Therapies. Excels in corporate strategy and high‑level stakeholder engagement, ensuring innovative treatments reach patients across diverse market archetypes.

Emmanuel Lo

Emmanuel Lo, MSc

CTO & Co-Founder

AI and analytics leader specializing in market access intelligence, platform development, and strategic decision support.

Educated at Columbia University (Master's in Management Science) and École des Ponts ParisTech (Diplôme d'Ingénieur, Finance). Founder of Access Explorer, he spearheads AI‑driven analytics to transform market‑access consulting worldwide.

Small team. Senior attention. High-impact delivery.

We are built for speed, precision, and accountability.

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Our Senior Advisors

Sarah Liu

Sarah Liu, MBA

Commercial Strategy Advisor

Sarah is a seasoned healthcare executive with over 20 years of commercial operations leadership in the pharmaceutical and biotechnology industry. She is Chief Commercial Officer at uMETHOD, a company that uses AI to improve healthcare delivery. Previously, she was Chief Commercial Officer at 9Meters Biopharma, a publicly held biotech focused on rare gastrointestinal diseases.

Prior to 9Meters, Ms. Liu was Vice President of Global Marketing and Vice President of New Product Planning at Novartis Gene Therapies. Earlier in her career, she held senior commercial leadership roles at Melinta Therapeutics, Takeda, and Abbott. Sarah earned an MBA from Wharton and a BA from Northwestern University.

Kimary Kulig

Kimary Kulig, PhD, MPH

Oncology Strategy Advisor

Kimary Kulig's professional career spans academic, non-profit, large pharma, and biotech start-up ecosystems. Owner and Principal of Kulig Consulting, she provides advice and services to companies developing oncology products. Additionally, she offers professional navigation services to cancer patients as My Biomarker Navigator®.

Kimary applied her unique training in immunology, molecular oncology, and epidemiology for 22 years at both Pfizer and Bristol Myers Squibb, between which she was Vice President at the National Comprehensive Cancer Network (NCCN) overseeing all operations of its Outcomes Research Database.

As Head of Oncology Clinical Research at Verily Life Sciences (Google), Kimary led digital pathology AI algorithm development. Kimary received her PhD from New York University's Institute of Graduate Biomedical Sciences and her MPH from Columbia University's Mailman School of Public Health.

Build the access strategy your product deserves.

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